U.S., May 29 -- ClinicalTrials.gov registry received information related to the study (NCT07612098) titled 'Preoperative Radiotherapy and Anlotinib With or Without Penpulimab for Soft Tissue Sarcoma' on May 21.
Brief Summary: Soft tissue sarcoma is a rare cancer that often requires surgery combined with radiotherapy. Preoperative radiotherapy can improve the chance of complete tumor removal and limb preservation, but some patients still experience local recurrence, distant metastasis, or poor tumor response.
This is a prospective, multicenter, randomized phase II study for patients with localized soft tissue sarcoma of the extremity or trunk who need preoperative radiotherapy. Participants will be randomly assigned to receive preoperative...