Clinical Trial: Platform Study of Targeted Therapies for Adults With Moderately to Severely Active Rheumatoid Arthritis

U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07904754) titled 'Platform Study of Targeted Therapies for Adults With Moderately to Severely Active Rheumatoid Arthritis' on Oct. 23.

Brief Summary: Rheumatoid arthritis (RA) is a chronic inflammatory disease that primarily affects the joints, causing pain, swelling, stiffness, and loss of function. Synovial fibroblasts play a key role in RA pathogenesis, with treatment-refractory patients demonstrating increased numbers of these cells. The goal of this study is to evaluate the safety and effectiveness of ABBV-2294 (a combination of ABBV-722 and upadacitinib) compared to each drug alone in treating moderately to severely active RA. The platform stud...