Clinical Trial: Phase I Study of In Vivo CAR-Tumor Technology for the Treatment of Advanced Malignant Tumors

U.S., Oct. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07859462) titled 'Phase I Study of In Vivo CAR-Tumor Technology for the Treatment of Advanced Malignant Tumors' on Sept. 30.

Brief Summary: This study is a single-arm, open-label, dose-escalation platform clinical trial designed to evaluate the safety, tolerability, efficacy, pharmacokinetic and pharmacodynamic characteristics of CAR-Tumour oncolytic virus as a vector platform for the treatment of advanced malignant tumours.

Subjects will be screened and assigned to cohorts based on target and indication:

Cohort A: Intratumoural injection or intravenous injection of CAR-Tumor05 solution for the treatment of advanced malignant solid tumours Co-group ...