U.S., April 14 -- ClinicalTrials.gov registry received information related to the study (NCT07525063) titled 'Pain & Reward Neuromodulation of CNS Circuits' on April 06.

Brief Summary: This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS). The study will assess preliminary efficacy and mechanisms of central nervous system changes using neuroimaging, behavioral tasks, sensory testing, and neuroimmune markers. Participants will undergo MRI scans, multi-day TMS sessions, and complete questionnaires. The goal is to generate pilot data for future trials on neuromodulation for chronic pain.

Study Start Date: May, 2026

Study Type: INTERV...