Clinical Trial: Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs

U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07902752) titled 'Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs' on Oct. 22.

Brief Summary: Drug overdose is a national crisis. The primary cause of death associated with opioids is opioid-induced respiratory depression. Naloxone (Narcan) which is the first line of defense for opioid overdose can reverse OIRD (Opioid-Induced Respiratory Depression), but in post-operative patients it will abolish pain control. There are no medications that can prevent OIRD. Pre-clinical studies provided evidence that intranasal (administered via a nasal spray) oxytocin may prevent and treat OIRD without interfering with pain control.

Study ...