U.S., Oct. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07864155) titled 'Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery' on May 29.

Brief Summary: This study will compare opioid-free anesthesia and opioid-based anesthesia in adult euthyroid patients undergoing elective thyroidectomy. Opioid-based anesthesia is commonly used during surgery, but opioids may be associated with adverse effects such as nausea, vomiting, respiratory depression, hyperalgesia, and increased postoperative opioid use. Opioid-free anesthesia uses non-opioid medications as part of a multimodal strategy to provide intraoperative analgesia.

The main aim of this prospective randomized study is to evaluate whether opioid-...