Clinical Trial: Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty

U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07770633) titled 'Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty' on Aug. 07.

Brief Summary: This study is a single-center, prospective, randomized, open-label clinical trial evaluating three commercially available closed-incision negative pressure wound therapy (ciNPWT) devices: NPseal, PICO, and Prevena, in adult patients undergoing primary total knee arthroplasty (TKA) who meet predefined high-risk criteria for wound complications.

A total of approximately 300 participants will be enrolled and randomized in a 1:1:1 fashion to receive one of the three study dressings applied over the closed surgical incision at the end of the p...