Clinical Trial: Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial Readiness

U.S., Aug. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07790302) titled 'Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial Readiness' on Aug. 24.

Brief Summary: This study will look at how many children develop rheumatic heart disease (RHD) over a 3-year period. The study will include children ages 5 to 8 who do not have RHD at the start and who live in areas where the disease is common. Each child will have a heart ultrasound (echocardiogram) once a year for 3 years to check for signs of RHD. Doctors will diagnose RHD using internationally recognized guidelines from the World Heart Federation (2023). The study will also look at how often new cases occur each year, whether...