U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07424508) titled 'Movement State-dependent Adaptive DBS for PD' on Feb. 13.
Brief Summary: This is a single-center clinical study aiming to improve gait functions in patients with Parkinson's Disease (PD) by using adaptive neurostimulation to the pallidum. The investigators will use a bidirectional deep brain stimulation device with sensing and stimulation capabilities to 1) identify neural biomarkers to detect the onset of walking by recording neural activities from the motor cortical areas and the globus pallidus, 2) understand the impacts of changes in DBS parameters on gait kinematics and optimize setting parameters for enhancing walking performa...