Clinical Trial: Mental Strategy Training in Mild Cognitive Impairment

U.S., July 23 -- ClinicalTrials.gov registry received information related to the study (NCT07718945) titled 'Mental Strategy Training in Mild Cognitive Impairment' on July 14.

Brief Summary: This study aims to reduce hippocampal activity in people at high risk of developing Alzheimer's disease (AD) and aims to examine whether this improves their episodic memory performance. We apply mental strategy trainings with strategies extracted from our previous study that applied real-time fMRI neurofeedback to reduce hippocampal activity. Participants take part in mental strategy trainings 2, 4, or 6 times. At baseline and after each 2 trainings, we assess their hippocampal activity as well as their episodic memory performance using an fMRI pattern...