U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07536516) titled 'Measurement of Ocular Blood Flow and Retinal Oxygen Extraction in Diabetic Patients' on June 30, 2025.
Brief Summary: The prevalence of diabetes is increasing, with type 2 diabetes mellitus comprising over 90% of cases. Diabetes mellitus complications, including diabetic retinopathy (DR), impose significant health burdens. GLP-1 receptor agonists (GLP-1RAs) and dual GIP/GLP-1 receptor agonists show promise in improving cardiovascular and kidney outcomes, but their effects on retinal microvasculature and neuroprotection remain unclear. This study investigates the impact of GLP-1RAs (semaglutide, liraglutide) and GIP/GLP-1-dual agoni...