U.S., June 30 -- ClinicalTrials.gov registry received information related to the study (NCT07672873) titled 'Local Dexamethasone Administration in Symptomatic Irreversible Pulpitis' on June 17.

Brief Summary: Symptomatic irreversible pulpitis is associated with a high incidence of inadequate pulpal anesthesia during endodontic treatment, particularly in mandibular molar teeth. Failure to achieve profound anesthesia may result in increased intraoperative pain and patient discomfort. Corticosteroids have been suggested as adjunctive agents to improve pain control and reduce inflammatory responses; however, the influence of different local administration techniques on anesthetic success and postoperative pain remains unclear.

The aim of this...