Clinical Trial: Liver Tumor Microenvironment Remodeling Promotes Hepatocellular Carcinoma Progression

U.S., Nov. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07937137) titled 'Liver Tumor Microenvironment Remodeling Promotes Hepatocellular Carcinoma Progression' on Nov. 08.

Brief Summary: Hepatocellular carcinoma (HCC) is a highly prevalent malignancy worldwide. Although radiofrequency ablation (RFA) is widely used for the treatment of early-stage small HCC, its 5-year recurrence rate reaches up to 70%, significantly higher than that of surgical resection, suggesting that the tumor microenvironment (TME) plays a critical role in the progression of residual tumors. Notably, in the context of non-alcoholic fatty liver disease (NAFLD), HCC patients with concurrent fatty liver have an even higher risk of post...