U.S., April 2 -- ClinicalTrials.gov registry received information related to the study (NCT07504601) titled 'Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers' on March 31.

Brief Summary: Background:

Opioid drugs are often prescribed for acute and chronic pain. But these drugs are addictive, and they lead to more than 14,000 overdose deaths in the United States each year. Researchers want to find new drugs that relieve pain but are not addictive. This study will test whether a single dose of an experimental drug called (2R,6R)-hydroxynorketamine (HNK) can help reduce short term pain in healthy adults. HNK is related to ketamine. Studies suggest HNK might be as effective as ketamine at reducing pain b...