Clinical Trial: INtubation With Sedation Only to Preserve Independent Respiratory Effort Trial

U.S., Sept. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07845305) titled 'INtubation With Sedation Only to Preserve Independent Respiratory Effort Trial' on Sept. 18.

Brief Summary: The INtubation with Sedation Only to Preserve Independent Respiratory Effort (INSPIRE) trial is a pragmatic, non-blinded, parallel-group, randomized clinical trial comparing the effect of intubation with sedation only (intervention group) versus intubation with sedation plus neuromuscular blockade (control group) among adults undergoing emergency tracheal intubation in the ED and ICU with regard to the outcomes of: (1) hypoxemia during intubation, (2) successful intubation on the first attempt, and (3) awake immobility and PT...