U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07424092) titled 'Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors' on Feb. 05.
Brief Summary: The goal of this clinical trial is to learn if intratumoral administration of DNX-2401 works to treat recurrent and refractory high grade brain tumors in children and young adults. It will also learn about the safety of DNX-2401.
The main questions it aims to answer are:
* Does a single intratumoral administration of DNX-2401 elicit tumor response and improve survival?
* Is a single intratumoral administration of DNX-2401 safe and well tolerated?
Participants will:
* Undergo surgery for tumor biopsy followed by a single intratumoral administ...