U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07490457) titled 'Intraoperative Ketamine for Chronic Postoperative Pain After Open-Heart Surgery' on March 13.
Brief Summary: The goal of this interventional study is to determine whether a single intraoperative IV dose of ketamine can reduce postoperative chronic and acute pain and postoperative opioid requirements in adult patients undergoing open-heart surgery under general anesthesia. The main questions it aims to answer are:
Primary outcome: Does a single-dose intraoperative IV ketamine reduce the presence and severity of pain at 3 and 6 months after surgery ? Secondary outcomes: Does it reduce acute postoperative pain scores, opioid consumpt...