U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07915739) titled 'Internal Mammary Node Irradiation After Neoadjuvant Systemic Therapy for Breast Cancer' on Oct. 28.
Brief Summary: This multicenter randomized controlled trial evaluates whether internal mammary node irradiation (IMNI) improves oncologic outcomes in patients with breast cancer who have residual pathologically positive lymph nodes after neoadjuvant systemic therapy.
Eligible participants will be randomly assigned in a 1:1 ratio to receive locoregional radiotherapy either with or without irradiation of the internal mammary lymph nodes. The primary outcome is disease-free survival. Secondary outcomes include overall survival, breast ca...