U.S., Aug. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07790146) titled 'Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation' on Aug. 24.
Brief Summary: Total knee arthroplasty (TKA) is the most effective treatment for stage III-IV knee osteoarthritis (OA). However, up to 30% of patients remain dissatisfied due to periarticular functional insufficiency, pain, and movement limitations. This study aims to improve TKA outcomes by developing and implementing a multimodal prehabilitation approach based on OA phenotypes (chronic pain, inflammatory, biomechanical) to correct clinical and functional disorders preoperatively, thereby enhancing postoperative recovery and quality...