U.S., Aug. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07764887) titled 'Impacted Tooth Management and Osteoradionecrosis Risk in NPC' on March 26.
Brief Summary: This multicenter, randomized controlled trial is designed to determine whether omitting prophylactic extraction of impacted teeth before radiotherapy leads to an unacceptably higher risk of jaw osteoradionecrosis (JORN) compared with conventional prophylactic extraction in patients with non-metastatic nasopharyngeal carcinoma (NPC). JORN is a condition in which jawbone tissue is damaged and fails to heal properly after radiotherapy.
A total of 536 eligible participants with at least one impacted tooth will be randomly assigned to either omit p...