Clinical Trial: Imaging CRF X NOP Interactions in Alcohol Use Disorder

U.S., May 30 -- ClinicalTrials.gov registry received information related to the study (NCT07612631) titled 'Imaging CRF X NOP Interactions in Alcohol Use Disorder' on May 16.

Brief Summary: This positron emission tomography imaging study uses [C-11]NOP-1A and hydrocortisone to image stress-modulating proteins in heavy drinking alcohol use disorder (AUD) subjects and healthy controls (HC). It will also characterize the role of these stress-regulating proteins in a relapse to alcohol.

Study Start Date: June 01

Study Type: INTERVENTIONAL

Condition: Alcohol Use Disorder

Intervention: RADIATION: Baseline [C-11]NOP-1A PET scan

Radiotracer

DRUG: Hydrocortisone

Intravenous, 1 mg/Kg

RADIATION: Post-hydrocortisone [C-11]NOP-1A PET scan

Ra...