U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT07569263) titled 'IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases' on April 29.
Brief Summary: This is a Phase I Study evaluating the safety and feasibility of IL-8 receptor-modified patient-derived activated CD70 CAR T cells in adult patients with brain metastases from primary cancer, with either newly diagnosed lesions or recurrent or progressive disease after prior therapy.
Study Start Date: July, 2026
Study Type: INTERVENTIONAL
Condition:
Brain Metastases
Intervention:
BIOLOGICAL: Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells
Single dose of 8R-7...