U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07916324) titled 'Hyaluronidase Injections for Sclerodactyly in Patients With Scleroderma' on Oct. 29.
Brief Summary: Systemic sclerosis can cause the skin of the fingers to become thick and tight, a condition called sclerodactyly. This can make it difficult to bend, straighten, and use the fingers. This study will evaluate whether intradermal injections of hyaluronidase (Amphadase) can improve hand mobility and function and will assess treatment-related side effects.
Approximately 10 adults with systemic sclerosis and sclerodactyly affecting both hands will participate at Stanford University. For each participant, one hand will be randomly selected ...