U.S., March 24 -- ClinicalTrials.gov registry received information related to the study (NCT07487688) titled 'Five-Year CT Follow-Up of Vertebral Fracture Risk Using Opportunistic Osteoporosis Screening' on March 17.
Brief Summary: This study evaluates whether opportunistic osteoporosis screening using routinely acquired computed tomography (CT) scans improves fracture risk prediction compared with guideline-recommended FRAX-based screening from age 50. In current practice, few high-risk individuals identified by FRAX actually receive confirmatory dual-energy X-ray absorptiometry (DXA), despite the growing health and economic burden of osteoporotic fractures. Volumetric bone mineral density (vBMD) and CT-based detection of vertebral fractu...