Clinical Trial: FABP4 Response After Roux-en-Y Gastric Bypass

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07774208) titled 'FABP4 Response After Roux-en-Y Gastric Bypass' on Aug. 12.

Brief Summary: This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months. Anthropometric, metabolic, and inflammatory parameters were assessed alongside FABP4, fasting GLP-1, and PYY. Patients were classified as FABP4 responders (decrease from baseline to 6 months) or rebound/non-responders. The study investigated whether FABP4 trajectory after RYGB is associated with the magnitude of weight loss, systemic inflammation, and...