U.S., April 8 -- ClinicalTrials.gov registry received information related to the study (NCT07515313) titled 'Expression of CD274 (PD-L1) and CD276 in B-cell Malignancies: A Study by Flowcytometry' on March 26.

Brief Summary: B-cell malignancies include a spectrum of cancers originating from abnormal B lymphocytes at different developmental stages (1) that affect the peripheral blood (PB), bone marrow (BM), and lymphatic system. They can be categorized into leukemias and lymphomas. Each has unique characteristics, depending on the type of cells affected, and different behaviors, ranging from chronic conditions with slow progression to aggressive forms that require immediate treatment (2).

Acute lymphoblastic leukemia (ALL) is the most comm...