Clinical Trial: Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain Injury

U.S., Oct. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07905937) titled 'Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain Injury' on Oct. 20.

Brief Summary: The study aims to enroll the small cell lung cancer(SCLC) who meet the indications for prophylactic cranial irradiation (PCI): patients with limited-stage SCLC who have achieved complete or partial remission after first-line treatment, or patients with extensive-stage SCLC whose tumors are effectively controlled after systemic therapy with no definitive evidence of brain metastases. Additional inclusion criteria are expected survival>=6 months, completion of at least 12 months of follow-up, and signed informed consent ob...