Clinical Trial: Evaluation of the Role of Serum Tenascin-X Levels in the Diagnosis of Hypermobile Ehlers-Danlos Syndrome

U.S., Oct. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07899554) titled 'Evaluation of the Role of Serum Tenascin-X Levels in the Diagnosis of Hypermobile Ehlers-Danlos Syndrome' on Sept. 30.

Brief Summary: Thirteen types of EDS have been described based on their clinical manifestations and genetic backgrounds. Their diagnosis relies on personal and family medical history, together with established clinical criteria. A definitive diagnosis can then be confirmed through genetic testing. However, definitive diagnosis of hypermobile Ehlers-Danlos syndrome (hEDS), the most common EDS subtype (>80% of cases), remains impossible because its molecular basis is still unknown.

The diagnosis of hEDS is based on a...