Clinical Trial: Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe

U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT07585890) titled 'Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe' on April 21.

Brief Summary: Machine perfusion (MP) has become routine clinical practice in liver transplantation. However, as the field has matured, direct randomized comparisons between distinct MP modalities have become increasingly impractical, given that donor and graft characteristics often predetermine the optimal preservation strategy. Consequently, many studies continue to reference historical benchmark cohorts from the pre-perfusion era, or use risk scores developed before routine utilization of MP. These cohorts, while o...