U.S., Oct. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07875140) titled 'Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART' on Oct. 02.
Brief Summary: Epigenetic clocks based on DNA methylation estimate biological age and are associated with age-related conditions, but they have not been validated for female fertility. This prospective, multicenter, observational, non-profit cohort study investigated whether epigenetic age, estimated from peripheral blood DNA methylation, differs between women undergoing in vitro fertilization (IVF/ICSI) who achieve a live birth and those who do not. In a predefined subgroup of 30 women under 40 years of age, epigenetic age was also assessed after ovarian s...