U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07480525) titled 'Efficacy and Mechanisms of Escitalopram in Drug-Naive First-Episode Major Depressive Disorder' on March 14.
Brief Summary: The goal of this project is to quantify the effectiveness and safety of escitalopram oxalate oral solution in the treatment of first-episode, drug-naive patients with major depressive disorder, and to explore the mechanisms underlying its antidepressant effects using multi-omics approaches. By integrating clinical, cognitive, laboratory, imaging, genetic, and environmental data, the study aims to identify patient subgroups who are most likely to benefit from escitalopram, thereby promoting individualized and pr...