U.S., June 30 -- ClinicalTrials.gov registry received information related to the study (NCT07674160) titled 'Effect of Simethicone on Colon Preparation During Water Exchange Colonoscopy' on March 03.

Brief Summary: Background: Colonoscopy reduces colorectal cancer mortality by enabling early detection and removal of adenomas. Its effectiveness, however, depends heavily on bowel preparation quality and mucosal visibility. Simethicone, an anti-foaming agent, decreases intraluminal bubbles and improves visualization; studies in conventional air-insufflation colonoscopy generally show benefits for cleanliness and patient comfort, but evidence in water-exchange (WE) colonoscopy remains limited.Objective: To evaluate whether adding oral simethic...