Clinical Trial: Effect of Early Transition to Assisted Ventilation on 28-day Successful Extubation in Critically Ill Patients

U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07519512) titled 'Effect of Early Transition to Assisted Ventilation on 28-day Successful Extubation in Critically Ill Patients' on March 30.

Brief Summary: EARLY-VENT is a multicenter, open-label, three-period cluster-randomized crossover trial designed to evaluate whether early transition from controlled to assisted ventilation improves outcomes in critically ill patients. The study will enroll approximately 1,600 adult patients across 10 ICUs who are expected to require mechanical ventilation for at least 48 hours and meet specific stability criteria (e.g., hemodynamically stable, light sedation). Participating centers will alternate between an e...