Clinical Trial: Early Versus Delayed Closure of Bladder Exstrophy in Female Patients

U.S., Sept. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07794540) titled 'Early Versus Delayed Closure of Bladder Exstrophy in Female Patients' on Aug. 24.

Brief Summary: This study compared two timings for primary single-stage surgery in female newborns with classic bladder exstrophy. Participants were randomly assigned to surgery within 72 hours of birth or at 6 to 12 weeks of age. Both groups received the same surgical repair and standardized perioperative care. The main outcome was successful closure of the bladder and abdominal wall 30 days after surgery. The study also evaluated wound dehiscence, surgical-site infection, urinary fistula, blood transfusion, reoperation, readmission, hospital stay, an...