U.S., Sept. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07844811) titled 'Early Redox Biomarker Changes After Stellate Ganglion Block in Traumatic Brain Injury' on Sept. 18.
Brief Summary: Oxidative stress is a key mediator of secondary brain injury after traumatic brain injury (TBI). The stellate ganglion block (SGB) has been shown to modulate cerebral hemodynamics and neuroinflammation in brain-injured patients, but its effect on circulating redox biomarkers in human TBI has not been studied.
This is a post hoc secondary analysis of stored paired arterial and internal jugular venous blood samples from a prospective, single-center, before-and-after pilot study conducted at the University Medical Centre...