U.S., Oct. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07885059) titled 'Dose-sparing Balanced Propofol Sedation in Colonoscopy' on Oct. 13.
Brief Summary: This randomized controlled trial compared two balanced propofol analgosedation strategies in adults undergoing elective colonoscopy. Participants were randomized to either a standard-dose protocol using an initial propofol dose of 1.0 mg/kg or a structured dose-sparing protocol using an initial propofol dose of 0.5 mg/kg. Both protocols included midazolam and fentanyl. The standard-dose protocol was anesthesiologist-guided, whereas the dose-sparing protocol was administered by a gastroenterologist trained in advanced life support and airway management...