U.S., Aug. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07791004) titled 'Deciphering Persistent Orofacial Pain - PIFP' on Aug. 18.
Brief Summary: Persistent non-dental orofacial pain is common yet poorly characterised, and its pathophysiology remains largely unknown. Two clinically similar entities are distinguished: post-traumatic trigeminal neuropathic pain (PTNP), in which peripheral nerve damage is demonstrable, and persistent idiopathic facial pain (PIFP), in which peripheral findings are typically absent - pointing to an altered central processing of trigeminal nociceptive input. This monocentric study characterises the peripheral and central mechanisms of PIFP by comparing PIFP patients with age- ...