Clinical Trial: Cross-cultural Adaptation and Validation of the Localised Scleroderma Quality of Life Instrument (LoSQI) in Juvenile Localised Scleroderma (JLS)

U.S., Oct. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07908108) titled 'Cross-cultural Adaptation and Validation of the Localised Scleroderma Quality of Life Instrument (LoSQI) in Juvenile Localised Scleroderma (JLS)' on Oct. 12.

Brief Summary: This international study adapts and validates the Localised Scleroderma Quality of Life Instrument (LoSQI) for children with JLS, a rare condition causing hardened skin and tissue.

Goals & Methods:

Workstream 1: Translates and culturally adapts LoSQI for multi-national use, pre-testing it with patients and families.

Workstream 2: Validates the tool through a prospective study of at least 100 patients across global centers (PRINTO, CARRA, PRES).

Impact: It cre...