Clinical Trial: Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)

U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07770100) titled 'Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)' on Aug. 10.

Brief Summary: This phase II, single arm study evaluates the feasibility and clinical outcomes of delivering stereotactic body radiation therapy (SBRT) to 6-10 metastatic lesions concurrently with standard-of-care immune checkpoint inhibitor therapy in patients with stage IV cancers, including head and neck, non-small cell lung cancers, cervical, esophageal, gastric and gastroesophageal cancers. The primary objective is to determine 6-month progression-free survival following concurrent treatme...