U.S., June 10 -- ClinicalTrials.gov registry received information related to the study (NCT07636057) titled 'Comparison of Effectiveness and Safety of Tofacitinib Versus Upadacitinib as Add-on to Methotrexate in Rheumatoid Arthritis' on April 29.

Brief Summary: The goal of this interventional study is to learn, whether Tofacitinib or upadacitinib is more effective in treating the patients of Rheumatoid Arthritis. It will also learn about the safety of these two agents. The main questions it aims to answer are:

* Which JAK inhibitor (Tofacitinib or Upadacitinib) is more effective to improve the disease activity of Rheumatoid arthritis in Pakistani population?

* What is the Disease Activity scores, ESR, CRP, RA factor level of patients?

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