Clinical Trial: Comparing Dextrose Prolotherapy vs. Sodium Hyaluronic Acid Injections for Jaw Joint Internal Derangement

U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07911358) titled 'Comparing Dextrose Prolotherapy vs. Sodium Hyaluronic Acid Injections for Jaw Joint Internal Derangement' on Oct. 25.

Brief Summary: This is a randomized comparative study to evaluate the effectiveness of two intra-articular injections for the management of Temporomandibular Joint (TMJ) internal derangement. The study compares Dextrose Prolotherapy (12.5%) versus Sodium Hyaluronic Acid. Sixty patients (30 per group) with clinically diagnosed TMJ internal derangement (Wilkes Stage II or III) who have not responded to conservative treatment will be enrolled. Participants will be randomly assigned to receive either a single 1ml intra-ar...