Clinical Trial: Color Change and Desensitization of Molar Incisor Hypomineralization-Affected Enamel Using Biomimetic Nano-Hydroxyapatite Toothpaste

U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07436039) titled 'Color Change and Desensitization of Molar Incisor Hypomineralization-Affected Enamel Using Biomimetic Nano-Hydroxyapatite Toothpaste' on Nov. 23, 2025.

Brief Summary: This clinical trial aims to evaluate if nano-hydroxyapatite (Nano-HA) toothpaste effectively treats children with Molar-Incisor Hypomineralization (MIH). It will also assess the safety of Nano-HA toothpaste. The main questions are:

* Does Nano-HA toothpaste reduce caries incidence, improve tooth aesthetics, and decrease hypersensitivity?

* How does Nano-HA compare to fluoridated toothpaste in terms of outcomes?

Participants will:

* Use Nano-HA or fluoridated toothp...