Clinical Trial: Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial)

U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07846579) titled 'Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial)' on Sept. 23.

Brief Summary: After surgery for benign prostatic hyperplasia (BPH) that physically removes the prostatic transition zone (such as TURP or laser enucleation), many men are routinely sent home with a 2- to 4-week prescription of an alpha-blocker (tamsulosin) to prevent urinary retention, even though the tissue targeted by the drug has been removed. Alpha-blockers can cause blood-pressure drops upon standing, fainting, and falls in older men.

In this study, men who have successfully undergone BPH surgery and passed an initial voiding trial a...