U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07438886) titled 'Catequentinib Hydrochloride (AL3818) Drug-Drug Interaction Study in Healthy Volunteers' on Feb. 11.
Brief Summary: This is a non-randomized, open-label, fixed-sequence drug-drug interaction study to evaluate the effects of itraconazole and ticagrelor on the pharmacokinetics of catequentinib hydrochloride (AL3818) in healthy volunteers.
Study Start Date: March 02
Study Type: INTERVENTIONAL
Condition:
Healthy Volunteer
Intervention:
DRUG: AL3818 Capsule
dosage form: capsule; strength: 8 mg; orally in fasted condition
DRUG: Itraconazole capsule
dosage form: capsule; strength: 0.1 g. Oral
DRUG: Ticagrelor Tablets
dosage form:...