Clinical Trial: BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in Children

U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07893444) titled 'BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in Children' on Oct. 13.

Brief Summary: The goal of this Phase II, multicenter, open-label, randomized controlled trial is to evaluate the efficacy and safety of short-course treatment regimens for children with non-severe, drug-susceptible pulmonary tuberculosis.

The main questions it aims to answer are:

* Do the 3-month bedaquiline, delamanid, contezolid, and pyrazinamide regimen (BDCZ) and the 4-month fixed-dose combination (FDC) regimen provide effective treatment, as measured by tuberculosis-free survival at 12 months after treatment initiation?

* ...