Clinical Trial: Brain Monitoring During PEEP-Based Respiratory Therapy in Critically Ill Patients

U.S., July 22 -- ClinicalTrials.gov registry received information related to the study (NCT07716787) titled 'Brain Monitoring During PEEP-Based Respiratory Therapy in Critically Ill Patients' on July 16.

Brief Summary: Mechanical ventilation is commonly used in critically ill patients with acute brain injury. Positive end-expiratory pressure (PEEP) and lung recruitment maneuvers are important ventilator strategies for improving oxygenation, but they may also influence cerebral blood flow, systemic hemodynamics, carbon dioxide levels, and brain electrical activity. The effects of PEEP-related ventilator changes on cortical function in neurocritical care patients remain insufficiently understood.

This prospective observational physiological...