Clinical Trial: Biomarkers of Type 1 Diabetes in Children and Their Healthy Siblings

U.S., June 5 -- ClinicalTrials.gov registry received information related to the study (NCT07627230) titled 'Biomarkers of Type 1 Diabetes in Children and Their Healthy Siblings' on May 30.

Brief Summary: This prospective observational cohort study evaluated genetic, immunologic, and environmental factors associated with type 1 diabetes in children. Children with newly diagnosed type 1 diabetes and their healthy siblings were enrolled between October 2017 and June 2021. Data collection included HLA class I and class II genotyping, measurement of diabetes-associated autoantibodies to insulin (IAA), glutamic acid decarboxylase (GADA), insulinoma-associated antigen-2 (IA-2A), zinc transporter 8 (ZnT8A), and islet cell antibodies (ICA), as well...