U.S., July 3 -- ClinicalTrials.gov registry received information related to the study (NCT07680140) titled 'Biomarker-Guided Antidepressant Selection' on June 25.

Brief Summary: Depression is one of the leading causes of disability worldwide. Common treatments like antidepressant medications and talk therapy work well for some people, but many others do not improve, even after trying multiple treatments.

This study will investigate two alternative treatment options for people whose depression has not responded to standard treatments: repetitive transcranial magnetic stimulation (rTMS), a non-invasive form of brain stimulation, and ketamine, a fast-acting medication. It can be difficult to decide between these interventions in clinical pra...