Clinical Trial: Bioequivalence of Sitagliptin/Metformin Tablets in Healthy Chinese Adults Under Fasting and Fed Conditions

U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07910682) titled 'Bioequivalence of Sitagliptin/Metformin Tablets in Healthy Chinese Adults Under Fasting and Fed Conditions' on Oct. 27.

Brief Summary: This study evaluated whether a test formulation of sitagliptin/metformin tablets (manufactured by Jiangxi Shimei Pharmaceutical Co., Ltd.) is bioequivalent to the reference product Janumet (sitagliptin phosphate/metformin hydrochloride tablets, MSD) in healthy Chinese adults. The study was conducted as two independent cohorts (fasting and fed) at a single centre. Each cohort used a randomised, open-label, two-period, two-sequence, single-dose crossover design with a 7-day washout between periods, and ...