U.S., June 30 -- ClinicalTrials.gov registry received information related to the study (NCT07674186) titled 'Autologous Fecal Microbiota Transplantation for Diversion Colitis' on June 15.
Brief Summary: Diversion colitis (DC) is a common inflammatory complication in patients with temporary ileostomy after rectal cancer surgery, and no standardized medical treatment exists. This prospective, assessor-blinded, parallel-group, randomized controlled trial evaluated whether autologous fecal microbiota transplantation (auto-FMT) delivered through the diverting stoma ameliorates DC and improves post-reversal outcomes. Sixty-six patients with endoscopically confirmed DC were randomized 1:1 to receive daily auto-FMT (n=33) or saline irrigation (n=3...